Evidence overview
Phase III-labelled hydrogen studies exist, but the label should not be mistaken for confirmatory evidence. The identified ClinicalTrials.gov records include four phase III studies and two combined phase II/III studies; their actual or intended enrollment ranges from 2 to 60 participants, and one is an uncontrolled pilot. A seventh study, Hydro-COVID, is called phase III in its peer-reviewed publication although its registry phase field is “Not applicable.” (Obesity registry, elderly cognition registry, Parkinson’s registry, stroke registry, rectal-cancer registry, transplantation registry, Hydro-COVID publication, Hydro-COVID registry.)
Molecular hydrogen: phase III and long-term clinical evidence (PDF 736KB)